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Axial spondyloarthritis (also often referred to as axSpA) is a chronic, immune-mediated disease predominantly affecting the axial skeleton (sacroiliac joints and spine). [1] The term itself is an umbrella term characterizing a diverse disease family united by shared clinical and genetic features, such as the involvement of the axial skeleton. [ 2 ]
When peripheral arthritis coexists with axial illness, conventional DMARDs such methotrexate, [37] sulfasalazine, [38] or leflunomide may be useful in treating peripheral spondyloarthritis. [39] These drugs are typically ineffective in treating axial symptoms of spondyloarthritis. [40]
About 50 percent of people can manage the symptoms of axSpA with over-the-counter pain relievers, says Dr. Reveille, whereas the other half, who have more advanced forms of axial spondyloarthritis ...
Ankylosing spondylitis is a member of the more broadly defined disease axial spondyloarthritis. [23] [24] Axial spondyloarthritis can be divided into two categories: radiographic axial spondyloarthritis (which is a synonym for ankylosing spondylitis) and non-radiographic axial spondyloarthritis (which include less severe forms and early stages ...
In the case of axial spondyloarthritis, corticosteroids are used to suppress the immune system, Dr. Troum says, adding that they’re designed to be used only for a brief period of time.
Managing axial spondyloarthritis (axSpA), an inflammatory form of arthritis that affects the spine and is sometimes also known as ankylosing spondylitis or AS, is always challenging.
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