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The peristimulus time histogram is sometimes called perievent time histogram, and post-stimulus and peri-stimulus are often hyphenated. The prefix peri, for through, is typically used in the case of periodic stimuli, in which case the PSTH show neuron firing times wrapped to one cycle of the stimulus.
The same stimulation sequence is repeated several times and the neuronal response is reported in a Peri-Stimulus-Time Histogram (PSTH). The time t is measured with respect to the start of the stimulation sequence.
The spike-triggered averaging (STA) is a tool for characterizing the response properties of a neuron using the spikes emitted in response to a time-varying stimulus. The STA provides an estimate of a neuron's linear receptive field. It is a useful technique for the analysis of electrophysiological data. Diagram showing how the STA is calculated.
Fig. 1. Neuron and myelinated axon, with signal flow from inputs at dendrites to outputs at axon terminals. The signal is a short electrical pulse called action potential or 'spike'. Fig 2. Time course of neuronal action potential ("spike"). Note that the amplitude and the exact shape of the action potential can vary according to the exact ...
Reconstruction refers to the ability of the researcher to predict what sensory stimuli the subject is receiving based purely on neuron action potentials. Therefore, the main goal of neural decoding is to characterize how the electrical activity of neurons elicit activity and responses in the brain.
The spike response model (SRM) [1] is a spiking neuron model in which spikes are generated by either a deterministic [2] or a stochastic [1] threshold process. In the SRM, the membrane voltage V is described as a linear sum of the postsynaptic potentials (PSPs) caused by spike arrivals to which the effects of refractoriness and adaptation are added.
In 1973, M. M. Taylor [1] suggested that if synapses were strengthened for which a presynaptic spike occurred just before a postsynaptic spike more often than the reverse (Hebbian learning), while with the opposite timing or in the absence of a closely timed presynaptic spike, synapses were weakened (anti-Hebbian learning), the result would be an informationally efficient recoding of input ...
[8] [3] These effects can be computed, in the case of advances or delays to responses, to observe the changes in the oscillatory behavior of neurons, pending on when a stimulus was applied in the phase cycle of an oscillating neuron. The key to understanding this is in the behavioral patterns of neurons and the routes neural information travels.