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A recent large-scale study found that severe depression in patients with bipolar disorder responds no better to a combination of antidepressant medications and mood stabilizers than it does to mood stabilizers alone and that antidepressant use does not hasten the emergence of manic symptoms in patients with bipolar disorder. [40]
It is known that even subclinical hypothyroidism can blunt a patient's response to both mood stabilizers and antidepressants. Furthermore, preliminary research into the use of thyroid augmentation in patients with refractory and rapid-cycling bipolar disorder has been positive, showing a slowing in cycle frequency and reduction in symptoms.
Antidepressants by themselves shouldn’t be used to treat bipolar disorder because they elevate the risk of triggering a manic episode. (Learn more about Antidepressants .)
Another possible problem with antidepressants is the chance of antidepressant-induced mania or hypomania in people with or without a diagnosis of bipolar disorder. Many cases of bipolar depression are very similar to those of unipolar depression. Therefore, the person can be misdiagnosed with unipolar depression and be given antidepressants ...
Escitalopram, a less recognizable term, is the generic name for this common prescription antidepressant. ... bipolar disorder, premenstrual dysphoric disorder (PMDD), post-traumatic stress ...
Toggle Bipolar Disorder subsection. 5.1 Mood Stabilizers. 5.2 Atypical Antipsychotics. ... 7.5 Sedating Antidepressants. 7.6 Antihistamines. 7.7 Others. 7.8 Non ...
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