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Herpes simplex 2, the virus usually responsible for genital herpes, can cause oral herpes infections, too—you might imagine how. Once infected with oral herpes, most people show no symptoms ...
(Reuters) -British drugmaker GSK said on Wednesday its experimental herpes simplex virus (HSV) vaccine candidate failed to meet the main goal of a mid-stage trial and would not be taken forward to ...
Pritelivir (development codes AIC316 or BAY 57-1293) is a direct-acting antiviral drug in development for the treatment of herpes simplex virus infections (HSV). This is particularly important in immune compromised patients. It is currently in Phase III clinical development by the German biopharmaceutical company AiCuris Anti-infective Cures AG.
Herpes simplex research includes all medical research that attempts to prevent, treat, or cure herpes, as well as fundamental research about the nature of herpes. Examples of particular herpes research include drug development , vaccines and genome editing.
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Talimogene laherparepvec is a genetically engineered herpes virus (an oncolytic herpes virus). Two genes were removed – one that shuts down an individual cell's defenses, and another that helps the virus evade the immune system – and a gene for human GM-CSF was added. The drug works by replicating in cancer cells, causing them to burst; it ...
NV1020 is an oncolytic herpes virus initially developed by Medigene Inc. and licensed for development by Catherex Inc. in 2010. [17] NV1020 has a deletion of just one copy of the ICP34.5 gene and ICP6 is intact. [1] A direct comparison of NV1020 and G207 in a mouse model of peritoneal cancer showed that NV1020 is more effective at lower doses. [18]
Herpes infections can lead to recurring, often painful, blisters. About half a billion people ages 15 to 49 have genital herpes infections, which are mostly caused by herpes simplex virus type 2 ...