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Organophosphate poisoning is poisoning due to organophosphates (OPs). [4] Organophosphates are used as insecticides, medications, and nerve agents. [4] Symptoms include increased saliva and tear production, diarrhea, vomiting, small pupils, sweating, muscle tremors, and confusion. [2]
A variety of mixed amido-alkoxo derivatives are known, one medically significant example being the anti-cancer drug cyclophosphamide. Also derivatives containing the thiophosphoryl group (P=S) include the pesticide malathion. The organophosphates prepared on the largest scale are the zinc dithiophosphates, as additives for
Organophosphate insecticides are acetylcholinesterase inhibitors, which disrupt the transmission of nerve signals in exposed organisms, with fatal results. The risk of human death through organophosphate poisoning [ 32 ] was obvious from the start and led to efforts to lower toxicity against mammals while not reducing efficacy against insects.
Pages in category "Organophosphate insecticides" The following 68 pages are in this category, out of 68 total. This list may not reflect recent changes. A.
Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. [3] It is a prodrug which is activated non-enzymatically into the active agent dichlorvos . It is used as an insecticide.
Cadusafos is an organothiophosphate, which is a subclass of organophosphates. Organophosphates can act as an inhibitor for acetylcholinesterase in a way for which the mechanism is known. [1] The active site of acetylcholinesterase contains an anionic site and an esteratic site.
Malathion is a pesticide that is widely used in agriculture, residential landscaping, public recreation areas, and in public health pest control programs such as mosquito eradication. [5] In the US, it is the most commonly used organophosphate insecticide. [6]
Dichlofenthion is an organophosphate insecticide that has been used in agricultural settings to control a variety of insect pests. The detailed uses, availability, and efficacy of dichlofenthion involve several aspects, including its application on crops, regulatory status, and effectiveness against pests.