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A variety of mixed amido-alkoxo derivatives are known, one medically significant example being the anti-cancer drug cyclophosphamide. Also derivatives containing the thiophosphoryl group (P=S) include the pesticide malathion. The organophosphates prepared on the largest scale are the zinc dithiophosphates, as additives for motor oil.
Pages in category "Organophosphate insecticides" The following 68 pages are in this category, out of 68 total. This list may not reflect recent changes. A.
Dimethoate is a widely used organophosphate insecticide and acaricide. It was patented and introduced in the 1950s by American Cyanamid. Like other organophosphates, dimethoate is an acetylcholinesterase inhibitor which disables cholinesterase, an enzyme essential for central nervous system function. It acts both by contact and through ingestion.
Methamidophos, trade name "Monitor," is an organophosphate insecticide.. Crops grown with the use of methamidophos include potatoes [1] and some Latin American rice. [2] Many nations have used methamidophos on crops, including developed nations such as Spain, United States, Japan, and Australia.
Organophosphate insecticides are acetylcholinesterase inhibitors, which disrupt the transmission of nerve signals in exposed organisms, with fatal results. The risk of human death through organophosphate poisoning [ 32 ] was obvious from the start and led to efforts to lower toxicity against mammals while not reducing efficacy against insects.
The health effects associated with organophosphate poisoning are a result of excess acetylcholine (ACh) present at different nerve synapses and neuromuscular junctions across the body. Specifically, acetylcholinesterase (AChE), the enzyme that normally and constantly breaks down acetylcholine, is inhibited by the organophosphate substance.
Malathion is a pesticide that is widely used in agriculture, residential landscaping, public recreation areas, and in public health pest control programs such as mosquito eradication. [5] In the US, it is the most commonly used organophosphate insecticide.
The United States Environmental Protection Agency (EPA), did publish a report on the safety concerns of Cadusafos used as a pesticide on bananas and concluded that “Potential acute and chronic dietary exposures from eating bananas treated with Cadusafos are below the level of concern for the entire U.S. population, including infants and ...