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Diazomethane is an organic chemical compound with the formula CH 2 N 2, discovered by German chemist Hans von Pechmann in 1894. It is the simplest diazo compound.In the pure form at room temperature, it is an extremely sensitive explosive yellow gas; thus, it is almost universally used as a solution in diethyl ether.
If excess diazomethane is present during the reaction, it can act as a base, abstracting a hydrogen from the diazonium-salt intermediate. The result is a neutral diazoketone, which does not react with the chloride. Instead, the byproduct, diazonium-methyl from the other diazomethane molecule, can be attacked by the chloride to produce ...
Diazo compounds have two main Lewis structures in resonance: R 2 >C-–N + ≡N and R 2 >CH=N + =N-. In organic chemistry, the diazo group is an organic moiety consisting of two linked nitrogen atoms at the terminal position.
CH 2 N 2 may refer to: . Cyanamide, an organic compound; Diazirine, class of organic molecules with a cyclopropene-like ring, 3H-diazirene; Diazomethane, chemical compound discovered in 1894
Cells with a defective G 2-M checkpoint will undergo apoptosis or death after cell division if they enter the M phase before repairing their DNA. [1] The defining biochemical feature of this checkpoint is the activation of M-phase cyclin-CDK complexes, which phosphorylate proteins that promote spindle assembly and bring the cell to metaphase. [2]
The entry and exit of large molecules from the cell nucleus is tightly controlled by the nuclear pore complexes (NPCs). Although small molecules can enter the nucleus without regulation, [ 1 ] macromolecules such as RNA and proteins require association with transport factors known as nuclear transport receptors , like karyopherins called ...
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
The Neuronal cell cycle represents the life cycle of the biological cell, its creation, reproduction and eventual death. The process by which cells divide into two daughter cells is called mitosis. Once these cells are formed they enter G1, the phase in which many of the proteins needed to replicate DNA are made. After G1, the cells enter S ...