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Sperm cells cannot divide and have a limited lifespan, but after fusion with egg cells during fertilization, a new organism begins developing, starting as a totipotent zygote. The human sperm cell is haploid, so that its 23 chromosomes can join the 23 chromosomes of the female egg to form a diploid cell with 46 paired chromosomes.
A single Sertoli cell extends from the basement membrane to the lumen of the seminiferous tubule, although the cytoplasmic processes are difficult to distinguish at the light microscopic level. Sertoli cells serve a number of functions during spermatogenesis, they support the developing gametes in the following ways:
Sertoli cells function to nourish the developing sperm cells. They secrete androgen-binding protein , a binding protein which increases the concentration of testosterone. There are two types: convoluted and straight, convoluted toward the lateral side, and straight as the tubule comes medially to form ducts that will exit the testis.
Spermatogenesis as the cells progress from spermatogium, to primary spermatocytes, to secondary spermatocytes, to spermatids and to sperm. Spermatocytes are a type of male gametocyte in animals. They derive from immature germ cells called spermatogonia. They are found in the testis, in a structure known as the seminiferous tubules. [1]
The sperm cell of Homo sapiens is the small reproductive cell produced by males, and can only survive in warm environments; upon leaving the body, it starts to degrade, thereby decreasing the total sperm quality. Sperm cells normally come in two types, "female" and "male", named for the resulting sex of the fertilized zygote each produces after ...
The overall structure of spermatozoa is very specialized as the cell has fully differentiated and matured. As spermatozoa, the cell no longer undergoes division. It consists of a head, midpiece, and flagella tail for motility. Head: As the head of the sperm, it is an ovular shape consisting of the nucleus and the acrosome. [4]
The testicles are two gonads that produce sperm by meiotic division of germ cells within the seminiferous tubules, [1] and synthesize and secrete androgens that regulate the male reproductive functions. The site of production of androgens is the Leydig cells that are located in the interstitium between seminiferous tubules. [1]
Because its main function is to nourish developing sperm cells through the stages of spermatogenesis, the Sertoli cell has also been called the "mother" or "nurse" cell. [10] Sertoli cells also act as phagocytes, consuming the residual cytoplasm during spermatogenesis. Translocation of cells from the basal lamina to the lumen of the ...