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The Kaplan–Meier estimator, [1] [2] also known as the product limit estimator, is a non-parametric statistic used to estimate the survival function from lifetime data. In medical research, it is often used to measure the fraction of patients living for a certain amount of time after treatment.
That is, 97% of subjects survive more than 2 months. Survival function 2. Median survival may be determined from the survival function: The median survival is the point where the survival function intersects the value 0.5. [4] For example, for survival function 2, 50% of the subjects survive 3.72 months. Median survival is thus 3.72 months.
This topic is called reliability theory, reliability analysis or reliability engineering in engineering, duration analysis or duration modelling in economics, and event history analysis in sociology. Survival analysis attempts to answer certain questions, such as what is the proportion of a population which will survive past a certain time?
Paul Meier (July 24, 1924 – August 7, 2011) [1] was a statistician who promoted the use of randomized trials in medicine. [2] [3]Meier is known for introducing, with Edward L. Kaplan, the Kaplan–Meier estimator, [4] [5] a method for measuring how many patients survive a medical treatment from one duration to another, taking into account that the sampled population changes over time.
It is used in survival theory, reliability engineering and life insurance to estimate the cumulative number of expected events. An "event" can be the failure of a non-repairable component, the death of a human being, or any occurrence for which the experimental unit remains in the "failed" state (e.g., death) from the point at which it changed on.
The Dirac comb of period 2 π, although not strictly a function, is a limiting form of many directional distributions. It is essentially a wrapped Dirac delta function. It represents a discrete probability distribution concentrated at 2 π n — a degenerate distribution — but the notation treats it as if it were a continuous distribution.
The image shows 2 curves that are identical to the figure on page 126 of First Aid for the USMLE Step 2 CK, 6th edition, by Le, Bushan, and Skapik. The text labels have been changed and color added, but the curves are exactly the same--even the tick marks correspond perfectly.
Corresponding methods can be used for a paired t-test and multiple comparisons. Similarly, for a regression analysis, an analyst would report the coefficient of determination (R 2) and the model equation instead of the model's p-value. However, proponents of estimation statistics warn against reporting only a few numbers.