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  2. Stevens–Johnson syndrome - Wikipedia

    en.wikipedia.org/wiki/StevensJohnson_syndrome

    The diagnosis of StevensJohnson syndrome is based on involvement of less than 10% of the skin. [2] It is known as TEN when more than 30% of the skin is involved and considered an intermediate form when 10–30% is involved. [3] SJS/TEN reactions are believed to follow a type IV hypersensitivity mechanism. [7]

  3. List of SJS-inducing substances - Wikipedia

    en.wikipedia.org/wiki/List_of_SJS-inducing...

    This is a list of drugs and substances that are known or suspected to cause StevensJohnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .

  4. Severe cutaneous adverse reactions - Wikipedia

    en.wikipedia.org/wiki/Severe_cutaneous_adverse...

    Stevens-Johnson/toxic epidermal necrolysis overlap syndrome (SJS/TEN); and Acute generalized exanthematous pustulosis (AGEP). The five disorders have similar pathophysiologies , i.e. disease-causing mechanisms, for which new strategies are in use or development to identify individuals predisposed to develop the SCARs-inducing effects of ...

  5. Toxic epidermal necrolysis - Wikipedia

    en.wikipedia.org/wiki/Toxic_epidermal_necrolysis

    Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a type of severe skin reaction. [2] Together with StevensJohnson syndrome (SJS) it forms a spectrum of disease, with TEN being more severe. [2] Early symptoms include fever and flu-like symptoms. [2] A few days later the skin begins to blister and peel forming painful raw ...

  6. Nikolsky's sign - Wikipedia

    en.wikipedia.org/wiki/Nikolsky's_sign

    StevensJohnson syndrome Nikolsky's sign is a clinical dermatological sign , named after Pyotr Nikolsky (1858–1940), a Russian physician who trained and worked in the Russian Empire. The sign is present when slight rubbing of the skin results in exfoliation of the outermost layer.

  7. Erythema multiforme major - Wikipedia

    en.wikipedia.org/wiki/Erythema_multiforme_major

    StevensJohnson syndrome (SJS) Toxic epidermal necrolysis (TEN) which described by Alan Lyell and previously called Lyell syndrome[5]. In this view, EM major, SJS and TEN are considered a single condition, distinguished by degree of epidermal detachment. [3] [4]

  8. Allopurinol hypersensitivity syndrome - Wikipedia

    en.wikipedia.org/wiki/Allopurinol...

    Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...

  9. Anticonvulsant hypersensitivity syndrome - Wikipedia

    en.wikipedia.org/wiki/Anticonvulsant...

    The hypersensitivity syndrome is characterized by a rash that is initially rash that appears similar to measles (morbilliform). [2]: 118 The rash may also be one of the potentially lethal severe cutaneous adverse reactions, the DRESS syndrome, StevensJohnson syndrome, or toxic epidermal necrolysis.