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Discoid lupus erythematosus is the most common type of chronic cutaneous lupus (CCLE), an autoimmune skin condition on the lupus erythematosus spectrum of illnesses. [1] [2] It presents with red, painful, inflamed and coin-shaped patches of skin with a scaly and crusty appearance, most often on the scalp, cheeks, and ears.
Neonatal lupus is the occurrence of SLE symptoms in an infant born from a mother with SLE, most commonly presenting with a rash resembling discoid lupus erythematosus, and sometimes with systemic abnormalities such as heart block or enlargement of the liver and spleen. [53]
Of these, systemic lupus erythematosus (also known as SLE) is the most common and serious form. A more thorough categorization of lupus includes the following types: [15] [16] [17] Childhood-onset systemic lupus erythematosus; acute cutaneous lupus erythematosus; subacute cutaneous lupus erythematosus; discoid lupus erythematosus (chronic ...
Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus, is a form of the chronic inflammatory and autoimmune disease, systemic lupus erythematosus (i.e., SLE), that develops in individuals up to 18 years old. [1]
Discoid lupus erythematosus: Skin ANA, Anti-dsDNA, Anti-Sm Confirmed Part of SLE prevalence (20-150 per 100,000) [11] Epidermolysis bullosa acquisita: Skin Anti-type VII collagen Confirmed Extremely rare [12] Erythema nodosum: Skin None specific Possible Not well established [13] Gestational pemphigoid: Skin Anti-BP180, Anti-BP230 Confirmed ...
It therefore isn’t the only trigger that’s thought to be associated with lupus—other potential triggers that have been associated with SLE include cigarette smoking, viruses, bacteria, use of certain medications like procainamide, hydralazine, and isoniazid, as well as sex hormones, particularly estrogen, which might be partly why lupus ...