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  2. Herpes simplex virus - Wikipedia

    en.wikipedia.org/wiki/Herpes_simplex_virus

    Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. [1] [2] Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus.

  3. Viral shedding - Wikipedia

    en.wikipedia.org/wiki/Viral_shedding

    Viral shedding is the expulsion and release of virus progeny following successful reproduction during a host cell infection. Once replication has been completed and the host cell is exhausted of all resources in making viral progeny, the viruses may begin to leave the cell by several methods.

  4. HSV epigenetics - Wikipedia

    en.wikipedia.org/wiki/HSV_epigenetics

    HSV epigenetics is the epigenetic modification of herpes simplex virus (HSV) genetic code.. As of 2012, an estimated 3.7 billion people globally were infected with oral herpes simplex virus (HSV-1), and 417 million were living with genital herpes (HSV-2) worldwide (World Health Organization, 2018).

  5. Herpes simplex virus 2 - Wikipedia

    en.wikipedia.org/wiki/Human_alphaherpesvirus_2

    In one study, daily genital swab samples found Herpes simplex virus 2 at a median of 12–28% of days among those who have had an outbreak, and 10% of days among those suffering from asymptomatic infection, with many of these episodes occurring without visible outbreak ("subclinical shedding"). [7]

  6. Herpetic gingivostomatitis - Wikipedia

    en.wikipedia.org/wiki/Herpetic_gingivostomatitis

    Herpetic gingivostomatitis is an infection caused by the herpes simplex virus (HSV). The HSV is a double-stranded DNA virus categorised into two types; HSV-1 and HSV-2.HSV-1 is predominantly responsible for oral, facial and ocular infections whereas HSV-2 is responsible for most genital and cutaneous lower herpetic lesions.

  7. Epigenetics of human herpesvirus latency - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_human...

    The lytic phase of infection occurs within mucoepithelial cells while the latent infection of these cells occurs in neurons. These two viruses are the cause of oral and genital herpes. [4] Latency is maintained in a variety of ways, one of which is the latency-associated transcript, or LAT. This long non-coding RNA accumulates in the latent ...

  8. Genital herpes - Wikipedia

    en.wikipedia.org/wiki/Genital_herpes

    About 16 percent of Americans between the ages of 14 and 49 are infected with genital herpes, making it one of the most common sexually transmitted infections. [26] More than 85% of those with HSV-2 are unaware of their infection. [27] Approximately 776,000 people in the United States get new herpes infections every year. [27]

  9. Viral replication - Wikipedia

    en.wikipedia.org/wiki/Viral_replication

    Viral replication is the formation of biological viruses during the infection process in the target host cells. Viruses must first get into the cell before viral replication can occur. Through the generation of abundant copies of its genome and packaging these copies, the virus continues infecting new hosts. Replication between viruses is ...

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