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Pharma giant Sanofi said its over-the-counter laxative, Dulcolax, is facing supply constraints. “Over the past few months, we have seen unprecedented demand for Dulcolax products," a Sanofi ...
[5] Macrogol came into use as a bowel prep in 1980 and was approved for medical use in the United States in 1999. [10] [11] [12] It is available as a generic medication and over the counter. [3] [13] In 2022, it was the 209th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
Bulk-forming laxatives, also known as roughage, are substances, such as fiber in food and hydrophilic agents in over-the-counter drugs, that add bulk and water to stools so they can pass more easily through the intestines (lower part of the digestive tract). [2] Properties. Site of action: small and large intestines; Onset of action: 12–72 hours
Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. [1] [5] The medication is taken by mouth or via the rectum. [1] [6] It typically begins working in around 30 minutes when given by rectum and within twelve hours when given by mouth. [3]
The main use is for treatment of constipation. In surgery it is used for pre-operative evacuation of the bowel. [3] In diagnostic testing it is used before x-ray examinations or physical examinations of the colon. It is safe for use in children. [4] If used in children under 3 years, it is recommended that the nozzle is only inserted half way. [5]
Functional constipation, also known as chronic idiopathic constipation (CIC), is defined by less than three bowel movements per week, hard stools, severe straining, the sensation of anorectal blockage, the feeling of incomplete evacuation, and the need for manual maneuvers during feces, without organic abnormalities.
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