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Samoyeds can be affected by basement membrane disease of the kidneys. It is inherited through the X chromosome and is therefore more severe in affected male dogs. Findings in male dogs include the presence of protein and glucose in the urine and the inability to concentrate urine, and progression to kidney failure by the age of 9 months and death by 16 months. [3]
What you might pay for common pet medical conditions. Condition. Average cost. Prevalence. Skin conditions. $200 to $2,500 • Number 1 in dogs (32% of claims)
Protein toxicity is the effect of the buildup of protein metabolic waste compounds, like urea, uric acid, ammonia, and creatinine.Protein toxicity has many causes, including urea cycle disorders, genetic mutations, excessive protein intake, and insufficient kidney function, such as chronic kidney disease and acute kidney injury.
Acetaminophen (paracetamol, Tylenol) can cause liver damage in dogs. The toxic dose is 150 mg/kg. [174] Ibuprofen * can cause gastrointestinal irritation, stomach ulcers, and kidney damage in dogs. [175] Naproxen (Aleve)* has a long half-life in dogs and can cause gastrointestinal irritation, anemia, melena (digested blood in feces), and vomiting.
[25] [29] [30] After 14 weeks of age, protein requirements decrease to 200 g/kg of diet (20% of the diet) for optimal growth. [6] [31] [32] [33] Protein in excess of these levels is metabolized and leads to an increase of the glomerular filtration rate, and increased urea excretion in the urine, with no evidence of damage to the kidneys. [34]
High dietary protein intake is not associated with kidney disease in healthy people. [322] While significantly increased protein intake in the short-term is associated with changes in renal function, there is no evidence to suggest this effect persists in the long-term and results in kidney damage or disease. [323]
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