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A mouse model has been developed. [4] This mouse model is characterized by a severe deficiency of ATR protein. [4] These mice have high levels of replicative stress and DNA damage. Adult Seckel mice display accelerated aging. [4] These findings are consistent with the DNA damage theory of aging.
Werner syndrome patients exhibit growth retardation, short stature, premature graying of hair, alopecia (hair loss), wrinkling, prematurely aged faces with beaked noses, skin atrophy (wasting away) with scleroderma-like lesions, lipodystrophy (loss of fat tissues), abnormal fat deposition leading to thin legs and arms, and severe ulcerations around the Achilles tendon and malleoli (around ankles).
The house mouse is best identified by the sharp notch in its upper front teeth. House mice have an adult body length (nose to base of tail) of 7.5–10 centimetres (3–4 in) and a tail length of 5–10 cm (2–4 in). The weight is typically 11–30 g (3 ⁄ 8 –1 oz).
In North America, Sin Nombre virus is the most common cause of HPS and is transmitted by the Eastern deer mouse (Peromyscus maniculatus). In South America, Andes virus is the most common cause of HPS and is transmitted mainly by the long-tailed pygmy rice rat (Oligoryzomys longicaudatus). In their rodent hosts, these hantaviruses cause a ...
Prognosis depends on the individual form of muscular dystrophy. Some dystrophies cause progressive weakness and loss of muscle function, which may result in severe physical disability and a life-threatening deterioration of respiratory muscles or heart. Other dystrophies do not affect life expectancy and only cause relatively mild impairment. [2]
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An analysis of data from more than 8,000 adults in the U.S. revealed that 14% had low iron blood levels, a condition known as absolute iron deficiency, while 15% had the right iron levels but ...
A mouse (pl.: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (Mus musculus). Mice are also popular as pets. In some places, certain kinds of field mice are locally common. They are ...