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In medicine, systolic hypertension is defined as an elevated systolic blood pressure (SBP). [1] If the systolic blood pressure is elevated (>140) with a normal (<90) diastolic blood pressure (DBP), it is called isolated systolic hypertension. [2] Eighty percent of people with systolic hypertension are over the age of 65 years old. [3]
Guidelines on the choice of agents and how best to step up treatment for various subgroups in hypertension (high blood pressure) have changed over time and differ between countries. A Comparison of International Guidelines on Goal Blood Pressure and Initial Therapy for Adults With Hypertension (adapted from JNC 8 guidelines [ 1 ] )
Normal. Less than 120 and. Less than 80. Elevated. 120-129 and. Less than 80. Stage 1 Hypertension. 130-139 or. 80-89. Stage 2 Hypertension. 140 or higher or. 90 or higher
For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
Blood pressure varies over longer time periods (months to years) and this variability predicts adverse outcomes. [18] Blood pressure also changes in response to temperature, noise, emotional stress , consumption of food or liquid, dietary factors, physical activity, changes in posture (such as standing-up ), drugs , and disease. [ 19 ]
The Systolic Blood Pressure Intervention Trial (SPRINT) is a multi-center clinical trial that was performed from 2010 to 2015, and published in November 2015. [1]The objective of the trial was to identify whether, in patients with a systolic blood pressure (SBP) of 130 mm Hg or higher and an increased cardiovascular risk, but without diabetes, treating to a systolic blood pressure target of ...