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Vitamin B 12 was discovered as a result of pernicious anemia, an autoimmune disorder in which the blood has a lower than normal number of red blood cells, due to a deficiency of vitamin B 12. [5] [16] The ability to absorb the vitamin declines with age, especially in people over 60. [17]
Adenosylcobalamin (AdoCbl), also known as coenzyme B 12, cobamamide, and dibencozide, is one of the biologically active forms of vitamin B 12. [1] Schematic diagram of the propionate metabolic pathway.
Pernicious anemia is the most common cause of vitamin B 12 deficiency anemia in adults, which results from malabsorption of vitamin B 12 due to a lack or loss of intrinsic factor. [ 2 ] [ 8 ] There are relatively few studies which have assessed the impact of haematological measures in response to B 12 supplementation.
In a trial on adult volunteers, this dose did not lead to a significant increase in serum vitamin B 12 levels when given thrice daily for one week. In addition, once-daily administration of 1 mg oral hydroxocobalamine caused the studied children's levels of homocysteine to increase and their levels of methionine to decrease, while the reverse ...
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Amchoor or aamchur or amchur, also referred to as mango powder, is a fruity spice powder made from dried unripe green mangoes. A citrusy seasoning, it is mostly produced in India . In addition to its use as a seasoning [ 1 ] [ 2 ] it adds the nutritional benefits of mangoes when the fresh fruit is out of season.