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Saccharomyces boulardii is a tropical yeast first isolated from lychee and mangosteen peels in 1923 by French scientist Henri Boulard. Although early reports claimed distinct taxonomic , metabolic, and genetic properties, [ 1 ] S. boulardii is a grouping of S. cerevisiae strains, all sharing a >99% genomic relatedness.
Henri Boulard was a French microbiologist who discovered the yeast Saccharomyces boulardii in 1923. He noticed people chewing on the skins of lychees and mangosteens to treat diarrhea during a cholera epidemic. He isolated and identified this strain of yeast, a probiotic. [1]
The strain Saccharomyces cerevisiae var. boulardii is industrially manufactured and used clinically as a medication. Several clinical and experimental studies have shown that S. cerevisiae var. boulardii is, to lesser or greater extent, useful for prevention or treatment of several gastrointestinal diseases. [71]
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