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  2. Myocardial contractility - Wikipedia

    en.wikipedia.org/wiki/Myocardial_contractility

    An increase in sympathetic stimulation to the heart increases contractility and heart rate. An increase in contractility tends to increase stroke volume and thus a secondary increase in preload. An increase in preload results in an increased force of contraction by Starling's law of the heart; this does not require a change in contractility.

  3. Cardiac glycoside - Wikipedia

    en.wikipedia.org/wiki/Cardiac_glycoside

    Cardiac glycoside. The general structure of a cardiac glycoside molecule. Cardiac glycosides are a class of organic compounds that increase the output force of the heart and decrease its rate of contractions by inhibiting the cellular sodium-potassium ATPase pump. [1]

  4. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    The resting heart rate of a newborn can be 120 beats per minute (bpm) and this gradually decreases until maturity and then gradually increases again with age. The adult resting heart rate ranges from 60 to 100 bpm. Exercise and fitness levels, age and basal metabolic rate can all affect the heart rate. An athlete's heart rate can be lower than ...

  5. Collagen - Wikipedia

    en.wikipedia.org/wiki/Collagen

    Collagen is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. [3] In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes 1% to 2% of muscle tissue and accounts for 6% of the weight to skeletal muscle. [4] The fibroblast is the most common cell creating collagen in ...

  6. Frank–Starling law - Wikipedia

    en.wikipedia.org/wiki/Frank–Starling_law

    The Frank–Starling law of the heart (also known as Starling's law and the Frank–Starling mechanism) represents the relationship between stroke volume and end diastolic volume. [1] The law states that the stroke volume of the heart increases in response to an increase in the volume of blood in the ventricles, before contraction (the end ...

  7. Bowditch effect - Wikipedia

    en.wikipedia.org/wiki/Bowditch_effect

    Bowditch effect. The Bowditch effect, also known as the Treppe phenomenon or Treppe effect or Staircase Phenomenon,[1][2] is an autoregulation method by which myocardial tension increases with an increase in heart rate. It was first observed by Henry Pickering Bowditch in 1871.