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2. Diabetic nephropathy - Wikipedia

   en.wikipedia.org/wiki/Diabetic_nephropathy

   Treatment. ACE inhibitors [4] Diabetic nephropathy, also known as diabetic kidney disease, [5] is the chronic loss of kidney function occurring in those with diabetes mellitus. Diabetic nephropathy is the leading causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) globally. The triad of protein leaking into the urine ...

3. Complications of diabetes - Wikipedia

   en.wikipedia.org/wiki/Complications_of_diabetes

   The complications of diabetes can dramatically impair quality of life and cause long-lasting disability. Overall, complications are far less common and less severe in people with well-controlled blood sugar levels. [3] [4] [5] Some non-modifiable risk factors such as age at diabetes onset, type of diabetes, gender, and genetics may influence risk.

4. Metformin - Wikipedia

   en.wikipedia.org/wiki/Metformin

   The most serious potential adverse effect of metformin is lactic acidosis; this complication is rare, and seems to be related to impaired liver or kidney function. [75] Metformin is not approved for use in those with severe kidney disease, but may still be used at lower doses in those with kidney problems. [76]

5. Why do some researchers believe metformin may hold the key to ...

   www.aol.com/lifestyle/why-researchers-believe...

   Some researchers are investigating how metformin, a common drug used to treat diabetes, may help prolong healthspan and lifespan. What evidence is there to support this notion?

6. Diabetes - Wikipedia

   en.wikipedia.org/wiki/Diabetes

   Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. [10][11] Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body becoming unresponsive to the hormone's effects. [12] Classic symptoms include thirst, polyuria ...

7. SGLT2 inhibitor - Wikipedia

   en.wikipedia.org/wiki/SGLT2_inhibitor

   SGLT2 inhibitors (also called gliflozins or flozins) are a class of medications that inhibit sodium-glucose transport proteins in the nephron (the functional units of the kidney), unlike SGLT1 inhibitors that perform a similar function in the intestinal mucosa. The foremost metabolic effect of this is to inhibit reabsorption of glucose in the ...