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  2. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    The US Food and Drug Administration (FDA) recommends avoiding the use of metformin in more severe chronic kidney disease, below the eGFR cutoff of 30 mL/minute/1.73 m 2. [87] Lactate uptake by the liver is diminished with metformin use because lactate is a substrate for hepatic gluconeogenesis, a process that metformin inhibits.

  3. Diabetes - Wikipedia

    en.wikipedia.org/wiki/Diabetes

    Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. [10][11] Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body becoming unresponsive to the hormone's effects. [12] Classic symptoms include thirst, polyuria ...

  4. Diabetic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_nephropathy

    Diabetic nephropathy, also known as diabetic kidney disease, [5] is the chronic loss of kidney function occurring in those with diabetes mellitus. Diabetic nephropathy is the leading causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) globally. The triad of protein leaking into the urine (proteinuria or albuminuria ...

  5. Think You Might Be Prediabetic? What to Know & Symptoms Look ...

    www.aol.com/think-might-prediabetic-know...

    If you do experience prediabetes symptoms, you may notice: Small skin growths. Darkened skin in your armpits or around your neck. Increased appetite. Unexplained weight loss or weight gain. High ...

  6. Why do some researchers believe metformin may hold the key to ...

    www.aol.com/lifestyle/why-researchers-believe...

    Some researchers are investigating how metformin, a common drug used to treat diabetes, may help prolong healthspan and lifespan. What evidence is there to support this notion?

  7. Diabetes management - Wikipedia

    en.wikipedia.org/wiki/Diabetes_management

    The first symptoms of gum and tooth infection in diabetic persons are decreased salivary flow and burning mouth or tongue. Also, patients may experience signs like dry mouth, which increases the incidence of decay. Poorly controlled diabetes usually leads to gum recession, since plaque creates more harmful proteins in the gums.