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A calibration curve plot showing limit of detection (LOD), limit of quantification (LOQ), dynamic range, and limit of linearity (LOL).. In analytical chemistry, a calibration curve, also known as a standard curve, is a general method for determining the concentration of a substance in an unknown sample by comparing the unknown to a set of standard samples of known concentration. [1]
Calibration can mean. a reverse process to regression, where instead of a future dependent variable being predicted from known explanatory variables, a known observation of the dependent variables is used to predict a corresponding explanatory variable; [1] procedures in statistical classification to determine class membership probabilities ...
Laboratory quality control is designed to detect, reduce, and correct deficiencies in a laboratory's internal analytical process prior to the release of patient results, in order to improve the quality of the results reported by the laboratory. Quality control (QC) is a measure of precision, or how well the measurement system reproduces the ...
The Standard addition method, often used in analytical chemistry, quantifies the analyte present in an unknown. This method is useful for analyzing complex samples where a matrix effect interferes with the analyte signal. In comparison to the calibration curve method, the standard addition method has the advantage of the matrices of the unknown ...
Size-exclusion chromatography, also known as molecular sieve chromatography, [ 1 ] is a chromatographic method in which molecules in solution are separated by their shape, and in some cases size. [ 2 ] It is usually applied to large molecules or macromolecular complexes such as proteins and industrial polymers. [ 3 ]
Calibration. In measurement technology and metrology, calibration is the comparison of measurement values delivered by a device under test with those of a calibration standard of known accuracy. Such a standard could be another measurement device of known accuracy, a device generating the quantity to be measured such as a voltage, a sound tone ...
Local regression or local polynomial regression, [1] also known as moving regression, [2] is a generalization of the moving average and polynomial regression. [3] Its most common methods, initially developed for scatterplot smoothing, are LOESS (locally estimated scatterplot smoothing) and LOWESS (locally weighted scatterplot smoothing), both pronounced / ˈ l oʊ ɛ s / LOH-ess.
The left plot, titled 'Concave Line with Log-Normal Noise', displays a scatter plot of the observed data (y) against the independent variable (x). The red line represents the 'Median line', while the blue line is the 'Mean line'. This plot illustrates a dataset with a power-law relationship between the variables, represented by a concave line.