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The NORD Rare Disease Database has over 1,300 reports on rare disorders. These reports provide detailed information about symptoms, causes, diagnosis, treatments, clinical trials, and support resources, including patient advocacy organizations.
In autoimmune blistering diseases, antibodies erroneously attack proteins that are essential for the layers of skin to stick (adhere) together. The specific symptoms and severity of blistering diseases vary from one person to another, even among individuals with the same disorder.
The Autoimmune Association is a national nonprofit organization dedicated to autoimmune disease awareness, advocacy, education, and research. The association supports research to find a cure for autoimmune diseases and provides services to affected individuals.
It is a rare autoimmune disorder of adulthood in which antibodies abnormally attack certain proteins on the surface of nerve endings that regulate calcium levels (calcium channels), resulting in inadequate release of acetylcholine.
Asherson’s syndrome is an extremely rare autoimmune disorder characterized by the development, over a period of hours, days or weeks, of rapidly progressive blood clots affecting multiple organ systems of the body.
NORD advances practical, meaningful, and enduring change so people with rare diseases can live their fullest and best lives. Every day, we elevate care, advance research, and drive policy in a purposeful and holistic manner to lift up the rare disease community.
Antiphospholipid syndrome (APS) is a rare autoimmune disorder characterized by recurring blood clots (thromboses). Blood clots can form in any blood vessel of the body. The specific symptoms and severity of APS vary greatly from person to person depending upon the exact location of a blood clot and the organ system affected.
Recent research suggests that the most probable cause of lichen sclerosus is an autoimmune reaction in genetically predisposed individuals. Affected populations. Lichen sclerosus affects mostly females, usually between the ages of 40 and 60 years. Females are six times as likely to be affected as are males.
Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenopathy, is a rare, benign (noncancerous, nonmalignant) disorder of the lymph nodes, predominantly of young adults and school aged children.
Numerous factors support that sIBM is an autoimmune disorder, especially the presence of certain inflammatory white blood cells in the muscle tissue of affected individuals. Autoimmune disorders occur when the body’s immune system mistakenly attacks healthy tissue.