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The cortical reaction is a process initiated during fertilization that prevents polyspermy, the fusion of multiple sperm with one egg.In contrast to the fast block of polyspermy which immediately but temporarily blocks additional sperm from fertilizing the egg, the cortical reaction gradually establishes a permanent barrier to sperm entry and functions as the main part of the slow block of ...
The process of spermatogenesis as the cells progress from primary spermatocytes, to secondary spermatocytes, to spermatids, to Sperm Cycle of the seminiferous epithelium of the testis Spermatocytogenesis is the male form of gametocytogenesis and results in the formation of spermatocytes possessing half the normal complement of genetic material.
Mammalian sperm cells become more active when they approach an egg cell in a process called sperm activation. Sperm activation has been shown to be caused by calcium ionophores in vitro , progesterone [ 2 ] released by nearby cumulus cells and binding to ZP3 of the zona pellucida.
Because its main function is to nourish developing sperm cells through the stages of spermatogenesis, the Sertoli cell has also been called the "mother" or "nurse" cell. [10] Sertoli cells also act as phagocytes, consuming the residual cytoplasm during spermatogenesis. Translocation of cells from the basal lamina to the lumen of the ...
The overall structure of spermatozoa is very specialized as the cell has fully differentiated and matured. As spermatozoa, the cell no longer undergoes division. It consists of a head, midpiece, and flagella tail for motility. Head: As the head of the sperm, it is an ovular shape consisting of the nucleus and the acrosome. [4]
Zona pellucida sperm-binding protein 3, also known as zona pellucida glycoprotein 3 (Zp-3) or the sperm receptor, is a ZP module-containing protein that in humans is encoded by the ZP3 gene. [5] ZP3 is the glycoprotein in the zona pellucida most important for inducting the acrosome reaction of sperm cells at the beginning of fertilization .
The acrosome is an organelle that develops over the anterior (front) half of the head in the spermatozoa (sperm cells) of humans and many other animals. It is a cap-like structure derived from the Golgi apparatus.
As sperm encounter the more alkaline environment of the female reproductive tract, CatSper channels become activated by the altered ion concentration. These channels are required for proper fertilization. [1] The study of these channels has been slow because they do not traffic to the cell membrane in many heterologous systems. [2]