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  2. New non-opioid painkiller approved by US health agency - AOL

    www.aol.com/non-opioid-painkiller-approved-us...

    A new type of non-opioid painkiller, aimed at treating short-term pain in adults, has been approved by the US Food and Drug Administration (FDA). The drug suzetrigine, known by its brand name ...

  3. FDA approves painkiller designed to eliminate the risk of ...

    www.aol.com/news/fda-approves-painkiller...

    It's the first new pharmaceutical approach to treating pain in more than 20 years, offering an alternative to both opioids and over-the-counter medications like ibuprofen and acetaminophen.

  4. FDA approves new type of non-opioid pain medication, 1st of ...

    www.aol.com/news/fda-approves-type-non-opioid...

    The drug, called Journavx (suzetrigine) and manufactured by biotech company Vertex Pharmaceuticals, is a non-opioid painkiller, which doesn’t have addictive properties, unlike opioids often used ...

  5. FDA approves painkiller designed to eliminate the risk of ...

    lite.aol.com/news/story/0001/20250131/b1dd4276...

    The new drug will carry a list price of $15.50 per pill, making it many times more expensive than comparable opioids, which are often available as generics for $1 or less. Vertex began researching the drug in the 2000s, when overdoses were rocketing upward, principally driven by mass prescribing of opioid painkillers for common ailments like ...

  6. Suzetrigine - Wikipedia

    en.wikipedia.org/wiki/Suzetrigine

    Suzetrigine, sold under the brand name Journavx, is a medication used for the management of pain. [1] [2] It is a non-opioid, small-molecule analgesic that works as a selective inhibitor of Na v 1.8-dependent pain-signaling pathways in the peripheral nervous system, [3] [4] avoiding the addictive potential of opioids.

  7. Is Vertex Pharmaceuticals a Buy Now That the FDA ... - AOL

    www.aol.com/vertex-pharmaceuticals-buy-now-fda...

    Journavx is a first-in-class non-opioid painkiller that acts on sodium channels in the peripheral nervous system. ... Journavx is the first new type of painkiller approved in more than 20 years ...

  8. Pain ladder - Wikipedia

    en.wikipedia.org/wiki/Pain_ladder

    The WHO guidelines recommend prompt oral administration of drugs ("by the mouth") when pain occurs, starting, if the patient is not in severe pain, with non-opioid drugs such as paracetamol (acetaminophen) or aspirin, [1] with or without "adjuvants" such as non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2 inhibitors.

  9. Codeine/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Codeine/paracetamol

    Codeine/paracetamol, also called codeine/acetaminophen and co-codamol, is a compound analgesic, comprising codeine phosphate and paracetamol (acetaminophen). Codeine/paracetamol is used for the relief of mild to moderate pain when paracetamol or non-steroidal anti-inflammatory drugs (NSAIDs; such as ibuprofen, aspirin, and naproxen) alone do not sufficiently relieve symptoms.