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  2. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Proton-pump inhibitors have largely superseded the H 2-receptor antagonists, a group of medications with similar effects but a different mode of action, and heavy use of antacids. [3] A potassium-competitive acid blocker (PCAB) revaprazan was marketed in Korea as an alternative to a PPI.

  3. Drugs for acid-related disorders - Wikipedia

    en.wikipedia.org/wiki/Drugs_for_acid-related...

    Proton-pump inhibitors are named using the suffix "-prazole". There is a purported correlation (but no proven causal link) between the use of PPIs and the risk of dementia. [ 6 ] However, this remain controversial as chronic and co-morbid pathology, and resultant polypharmacy (including increased consumption of PPIs), will probably itself also ...

  4. Omeprazole - Wikipedia

    en.wikipedia.org/wiki/Omeprazole

    Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs. [9] It can be taken by mouth or by injection into a vein . [ 1 ] [ 10 ] It is also available in the fixed-dose combination medication omeprazole/sodium bicarbonate as Zegerid [ 11 ] [ 12 ] and as Konvomep.

  5. FDA Approves New GERD Treatment Vonoprazan for ... - AOL

    www.aol.com/fda-approves-gerd-treatment...

    Proton pump inhibitors (PPIs) relieve symptoms of GERD by reducing the production of acid in the stomach. They include lansoprazole (Prevacid 24 HR), omeprazole (Prilosec) and esomeprazole (Nexium).

  6. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Proton pump inhibitors (PPIs) block the gastric hydrogen potassium ATPase (H + /K + ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid-related diseases, including gastroesophageal reflux disease (GERD) and peptic ulcer disease. PPIs also can bind to other types of proton pumps such as those ...

  7. Pantoprazole - Wikipedia

    en.wikipedia.org/wiki/Pantoprazole

    Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion. [5] It works by inactivating (H+/K+)-ATPase function in the stomach. [9] [5] The study of pantoprazole began in 1985, and it came into medical use in Germany in 1994. [10] It is available as a generic medication.

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