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This indicates that increasing CREB reverses the positive effects of cocaine. Northern blot analysis several days after CREB overexpression showed a marked increase in dynorphin mRNA in the nucleus accumbens. [18] Blocking KORs with an antagonist (norBNI) blocked the aversive effects caused by CREB overexpression. [18]
Cocaine (from French cocaïne, from Spanish coca, ultimately from Quechua kúka) [13] is a tropane alkaloid that acts as a central nervous system (CNS) stimulant. As an extract, it is mainly used recreationally and often illegally for its euphoric and rewarding effects.
In comparison, a typical dose (a "line") of cocaine contains between 20 and 30 milligrams. [2]) Owing to the presence of these alkaloids, coca tea is a mild stimulant ; its consumption may be compared to consumption of a moderately strong cup of coffee or tea. [ 3 ]
Cocaine is a highly addictive stimulant and a Schedule II drug. There are long and short-term effects to users of the drug. According to American Addiction Centers, here is what the effects of ...
Sharks living off the coast of Brazil have tested positive for cocaine, according to new research, the first time that the drug has been detected in free-ranging sharks.. Scientists tested 13 ...
In 1999, Hart began investigating the effects of crack cocaine on behavior. [2] Through 2009, ... recreational use of drugs has a positive effect, ...
Dimethocaine is often abused as a legal substitute for cocaine. The drug is administered intravenously or nasally, because ingestion would lead to rapid hydrolyzation. [5] Its positive effects are euphoria, stimulation, increased talkativeness and mood lift. [6] However, because the drug acts similar as cocaine, it has comparable negative side ...
All samples tested positive, with cocaine concentrations up to 100 times higher than those previously reported in other aquatic species. ... “Considering the psychotropic effects of drugs of ...