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  2. Letrozole - Wikipedia

    en.wikipedia.org/wiki/Letrozole

    Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer for post-menopausal women. [ 1 ] It was patented in 1986 and approved for medical use in 1996. [ 4 ]

  3. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    Although benzodiazepines can put people to sleep, while asleep, the drugs disrupt sleep architecture, decreasing sleep time, delayed and decreased REM sleep, increased alpha and beta activity, decreased K complexes and delta activity, and decreased deep slow-wave sleep (i.e., NREM stages 3 and 4, the most restorative part of sleep for both ...

  4. Aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Aromatase_inhibitor

    Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...

  5. Insomnia - Wikipedia

    en.wikipedia.org/wiki/Insomnia

    A sleep diary can be used track time to bed, total sleep time, time to sleep onset, number of awakenings, use of medications, time of awakening, and subjective feelings in the morning. [95] The sleep diary can be replaced or validated by the use of out-patient actigraphy for a week or more, using a non-invasive device that measures movement.

  6. Sleep deprivation - Wikipedia

    en.wikipedia.org/wiki/Sleep_deprivation

    A well-rested and healthy individual will generally spend less time in the REM stage of sleep. Studies have shown an inverse relationship between time spent in the REM stage of sleep and subsequent wakefulness during waking hours. [24] Short-term insomnia can be induced by stress or when the body experiences changes in environment and regimen. [25]

  7. Ramelteon - Wikipedia

    en.wikipedia.org/wiki/Ramelteon

    Ramelteon, sold under the brand name Rozerem among others, is a melatonin agonist medication which is used in the treatment of insomnia. [3] [5] It is indicated specifically for the treatment of insomnia characterized by difficulties with sleep onset. [3] It reduces the time taken to fall asleep, but the degree of clinical benefit is small. [6]

  8. Hypersomnia - Wikipedia

    en.wikipedia.org/wiki/Hypersomnia

    Sleep apnea can occur 10 times as often in uremic patients than in the general population and can affect up to 30-80% of patients on dialysis, though nighttime dialysis can improve this. About 50% of dialysis patients have hypersomnia, as severe kidney disease can cause uremic encephalopathy, increased sleep-inducing cytokines , and impaired ...

  9. Sleep state misperception - Wikipedia

    en.wikipedia.org/wiki/Sleep_state_misperception

    Sleep state misperception (SSM) is a term in the International Classification of Sleep Disorders (ICSD) most commonly used for people who mistakenly perceive their sleep as wakefulness, [1] [2] though it has been proposed that it can be applied to those who severely overestimate their sleep time as well [3] ("positive" sleep state misperception). [4]