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  2. Amitriptyline - Wikipedia

    en.wikipedia.org/wiki/Amitriptyline

    Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. [12]

  3. Your Guide to the 6 Most Common Types of Depression ... - AOL

    www.aol.com/6-types-depression-medications...

    Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...

  4. Serotonin–norepinephrine–dopamine reuptake inhibitor

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    Although two-thirds of patients will ultimately respond to antidepressant treatment, one-third of patients respond to placebo, [20] and remission is frequently sub-maximal (residual symptoms). In addition to post-treatment relapse, depressive symptoms can even recur in the course of long-term therapy ( tachyphylaxis ).

  5. Milnacipran - Wikipedia

    en.wikipedia.org/wiki/Milnacipran

    During its development for fibromyalgia, milnacipran was evaluated utilizing a composite responder approach.To be considered as a responder for the composite ‘treatment of fibromyalgia’ endpoint, each patient had to show concurrent and clinically meaningful improvements in pain, physical function, and global impression of disease status.

  6. Duloxetine - Wikipedia

    en.wikipedia.org/wiki/Duloxetine

    Duloxetine, tricyclic antidepressants, and anticonvulsants have similar tolerability while opioids cause more side effects. [34] Another review in Prescrire International considered the moderate pain relief achieved with duloxetine to be clinically insignificant and the results of the clinical trials unconvincing.

  7. Desipramine - Wikipedia

    en.wikipedia.org/wiki/Desipramine

    Desipramine, sold under the brand name Norpramin among others, is a tricyclic antidepressant (TCA) used in the treatment of depression. [8] It acts as a relatively selective norepinephrine reuptake inhibitor, though it does also have other activities such as weak serotonin reuptake inhibitory, α 1-blocking, antihistamine, and anticholinergic effects.

  8. Tricyclic antidepressant - Wikipedia

    en.wikipedia.org/wiki/Tricyclic_antidepressant

    The TCAs are used primarily in the clinical treatment of mood disorders such as major depressive disorder (MDD), dysthymia, and treatment-resistant variants. They are also used in the treatment of a number of other medical disorders, including cyclic vomiting syndrome (CVS) and anxiety disorders such as generalized anxiety disorder (GAD), social phobia (SP) also known as social anxiety ...

  9. Trimipramine - Wikipedia

    en.wikipedia.org/wiki/Trimipramine

    The side effects of trimipramine have been said to be similar to those of other tertiary amine TCAs, with a preponderance of anticholinergic and sedative effects. [9] However, trimipramine has also been said to be associated with a different side effect profile compared to other TCAs and in general with fewer side effects, chiefly due to its lack of norepinephrine reuptake inhibition and ...