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Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine. [4] The recommended strength solution contains 10% Povidone, with total iodine species equaling 10,000 ppm or 1% total titratable iodine. [4] It works by releasing iodine which results in the death of a range of microorganisms. [1]
Medical iodophor (Chinese povidone-iodine solution) An iodophor is a preparation containing iodine complexed with a solubilizing agent, such as a surfactant or water-soluble polymers such as povidone (forming povidone-iodine), [1] [2] The result is a water-soluble material that releases free iodine when in solution.
USP Tincture of Iodine is defined in the U.S. National Formulary (NF) as containing in each 100 mL, 1.8 to 2.2 grams of elemental iodine, and 2.1 to 2.6 grams of sodium iodide. Alcohol is 50 mL, and the balance is purified water. This "2% free iodine" solution has 0.08 mol/L of I 2, which provides about 1 mg of free iodine per 0.05 mL drop. The ...
The povidone iodine contains 10% available iodine, slowly released when applied to skin. This preparation is employed topically as a surgical scrub and non irritating antiseptic solution; its effectiveness is directly attributed to the presence and release of iodine from the complex. Commercial product: Betadine solution. [20]
The most commonly used (nominal) 5% solution consists of 5% iodine (I 2) and 10% potassium iodide (KI) mixed in distilled water and has a total iodine content of 126.4 mg/mL. The (nominal) 5% solution thus has a total iodine content of 6.32 mg per drop of 0.05 mL; the (nominal) 2% solution has 2.53 mg total iodine content per drop.
iodine preparations, such as iodopovidone in various galenics (ointment, solutions, wound plasters), in the past also Lugol's solution, peroxides such as urea perhydrate solutions and pH-buffered 0.1 – 0.25% peracetic acid solutions, alcohols with or without antiseptic additives, used mainly for skin antisepsis,