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Prostaglandin D 2 receptor 2 (DP 2 or CRTH2) is a human protein encoded by the PTGDR2 gene. [5] DP 2 has also been designated as CD294 (cluster of differentiation 294). It is a member of the class of prostaglandin receptors which bind with and respond to various prostaglandins. DP 2 along with prostaglandin DP 1 receptor are receptors for ...
The PTGDR gene that encodes the prostaglandin D 2 receptor in humans is found on the long arm of chromosome 14 at 14q22.1 and consists of four exons. [3] A 1995 molecular cloning study of the prostaglandin D2 receptor derived from humans found that the corresponding cDNA encoded for a protein with 359 amino acids and molecular mass of 40,276 daltons. [4]
Arguably the most important of the Phase II (conjugative) enzymes, UGTs have been the subject of increasing scientific inquiry since the mid-to-late 1990s. The reaction catalyzed by the UGT enzyme involves the addition of a glucuronic acid moiety to xenobiotics and is the most important pathway for the human body's elimination of the most ...
In the absence of pRb, E2F1 (along with its binding partner DP1) mediates the trans-activation of E2F1 target genes that facilitate the G1/S transition and S-phase. E2F targets genes that encode proteins involved in DNA replication (for example DNA polymerase , thymidine kinase , dihydrofolate reductase and cdc6 ), and chromosomal replication ...
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human major histocompatibility complex, class II, DP alpha 1 Identifiers Symbol HLA-DPA1 Alt. symbols HLA-DP1A NCBI gene 3113 HGNC 4938 OMIM 142880 RefSeq NM_033554 UniProt P20036 Other data Locus Chr. 6 p21.3 Search for Structures Swiss-model ...
HLA-DP is a protein/peptide-antigen receptor and graft-versus-host disease antigen that is composed of 2 subunits, DPα and DPβ. DPα and DPβ are encoded by two loci, HLA-DPA1 and HLA-DPB1, that are found in the MHC Class II (or HLA-D) region in the Human Leukocyte Antigen complex on human chromosome 6 (see protein boxes on right for links).
In molecular biology, transcription factor DP (Dimerization Partner) is a family of proteins which function as transcription factors.
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