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The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.
Fundic gland polyposis is a medical syndrome where the fundus and the body of the stomach develop many fundic gland polyps.The condition has been described both in patients with familial adenomatous polyposis (FAP) and attenuated variants (AFAP), and in patients in whom it occurs sporadically.
The proton pump is the terminal stage in gastric acid secretion, being directly responsible for secreting H + ions into the gastric lumen, making it an ideal target for inhibiting acid secretion. [ citation needed ] Because the H,K-ATPase is the final step of acid secretion, an inhibitor of this enzyme is more effective than receptor ...
Esomeprazole, sold under the brand name Nexium [or Neksium] among others, [2] is a medication which reduces stomach acid. [11] It is used to treat gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. [11] [12] Its effectiveness is similar to that of other proton pump inhibitors (PPIs). [13]
Acid reflux into the mouth can cause breakdown of the enamel, especially on the inside surface of the teeth. A dry mouth, acid or burning sensation in the mouth, bad breath and redness of the palate may occur. [27] Less common symptoms of GERD include difficulty in swallowing, water brash, chronic cough, hoarse voice, nausea and vomiting. [26]
Heartburn, also known as pyrosis, cardialgia or acid indigestion, [2] is a burning sensation in the central chest or upper central abdomen. [3] [4] [5] Heartburn is usually due to regurgitation of gastric acid (gastric reflux) into the esophagus. It is the major symptom of gastroesophageal reflux disease (GERD). [6]
A reflux suppressant is any one of a number of drugs used to combat oesophageal reflux. [1] [2] Commonly, following ingestion a 'raft' of alginic acid is created, floating on the stomach contents by carbon dioxide released by the drug. This forms a mechanical barrier to further reflux. Some preparations also contain antacids to protect the ...
The treatment of lymphocytic esophagitis is still undefined. [5] Treatment either targets symptoms, inflammation or complications. For example, heartburn is a symptom in lymphocytic esophagitis, and proton pump inhibitors , which reduce acidity in the stomach, are consequently used for treatment.
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