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Williams lost her partner to a decades-long struggle with depression in 2015 and for more than 20 years has focused her work on individualized mental health care. Mapping depression in the brain
The earliest and most widely known scientific theory of antidepressant action is the monoamine hypothesis, which can be traced back to the 1950s and 1960s. [200] [201] This theory states that depression is due to an imbalance, most often a deficiency, of the monoamine neurotransmitters, namely serotonin, norepinephrine, and/or dopamine.
The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
The neurotrophic hypothesis of depression [1] proposes that major depressive disorder (MDD) is caused, at least partly, by impaired neurotrophic support.Neurotrophic factors (also known as neurotrophins) are a family of closely related proteins which regulate the survival, development, and function of neurons in both the central and peripheral nervous systems.
Dimethyltryptamine is a powerful hallucinogenic found in several plants and is the psychoactive compound found in ayahuasca.
This soon became the standard measure of hopelessness, though it was less used than the long existing Beck Depression Inventory. In 1988 and 1989, Abramson, Gerald Metalsky, Lauren Alloy and Shirley Hartlage revised Abramson's 1978 work, and named the results the "hopelessness theory of depression". They believed that "hopelessness depression ...
With more chronic forms of depression, the most effective treatment is often considered to be a combination of medication and psychotherapy. [6] [9] Psychotherapy is the treatment of choice in people under 18. [8] A meta-analysis examined the effectiveness of psychotherapy for depression across ages from younger than 13 years to older than 75 ...