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My dog Buster has the skin condition vitiligo. It causes depigmentation of the skin (and fur). These photos beautifully capture how vitiligo has made Buster even more unique: November 2021 ...
Incidences of autoimmune skin diseases can vary based on several factors. Some of these factors include the breed, age, and sex of the dog, along with individual genetics and environmental factors. [3] In terms of vitiligo, certain breeds of dogs have a higher chance of developing the disease based on their genetics.
The post Black Dog ‘Buster’ Turns White Due To Rare Genetic Condition appeared first on DogTime. ... The reason behind Buster’s drastic change is vitiligo, a genetic condition often seen in ...
Some genetic conditions that result in a "leucistic" appearance include piebaldism, Waardenburg syndrome, vitiligo, Chédiak–Higashi syndrome, flavism, isabellinism, xanthochromism, axanthism, amelanism, and melanophilin mutations. Pale patches of skin, feathers, or fur (often referred to as "depigmentation") can also result from injury.
Research indicates that the majority of variation in coat growth pattern, length and curl can be attributed to mutations in four genes, the R-spondin-2 gene or RSPO2, the fibroblast growth factor-5 gene or FGF5, the keratin-71 gene or KRT71 [15] and the melanocortin 5 receptor gene (MC5R). The wild-type coat in dogs is short, double and straight.
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Type 2E is caused by an autosomal dominant mutation in the gene SOX10. [4] Rarely, a mutation in a gene other than those currently known may be responsible for a Waardenburg syndrome with features of type 2. This is usually initially classified as simply type 2 but may be given its own subtype once a gene or locus is identified and established. [7]
Naproxen (Aleve)* has a long half-life in dogs and can cause gastrointestinal irritation, anemia, melena (digested blood in feces), and vomiting. [175] Antifreeze* is very dangerous to dogs and causes central nervous system depression and acute kidney injury. Treatment needs to be within eight hours of ingestion to be successful. [174]