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Brugia malayi is a filarial (arthropod-borne) nematode (roundworm), one of the three causative agents of lymphatic filariasis in humans. Lymphatic filariasis, also known as elephantiasis , is a condition characterized by swelling of the lower limbs.
Brugia is a genus for a group of small roundworms. They are among roundworms that cause the parasitic disease filariasis. [1] Specifically, of the three species known, Brugia malayi and Brugia timori cause lymphatic filariasis in humans; and Brugia pahangi and Brugia patei infect domestic cats, dogs and other animals.
Lymphatic filariasis is caused by the worms Wuchereria bancrofti, Brugia malayi, and Brugia timori. These worms occupy the lymphatic system, including the lymph nodes; in chronic cases, these worms can lead to the syndrome of elephantiasis. Loiasis a subcutaneous filariasis is caused by Loa loa (the eye worm).
Three species of filarial roundworms, all from the Onchocercidae family, cause human lymphatic filariasis: Wuchereria bancrofti, Brugia malayi, and Brugia timori. [1] Tropical pulmonary eosinophilia is a rare syndrome characterised by pulmonary interstitial infiltrates and marked peripheral eosinophilia. [2]
Wuchereria bancrofti is a filarial (arthropod-borne) nematode (roundworm) that is the major cause of lymphatic filariasis.It is one of the three parasitic worms, together with Brugia malayi and B. timori, that infect the lymphatic system to cause lymphatic filariasis.
Brugia timori is a filarial (arthropod-borne) nematode (roundworm) which causes the disease "Timor filariasis", or "Timorian filariasis". While this disease was first described in 1965, [ 1 ] the identity of Brugia timori as the causative agent was not known until 1977. [ 2 ]
Microfilaria of Dirofilaria immitis (heartworms) in a lymph node impression smear from a dog with lymphoma. This baby nematode is snuggled down in a pillow of intermediate-to-large, immature lymphocytes, exhibiting multiple criteria of malignancy (1,000X magnification; courtesy Lance Wheeler) Microfilaria found in blood slides LACEN State Laboratory of Amazonas Brazil
Brugia malayi; Brugia timori; Wuchereria bancrofti [7] Three other medically important parasitic species are: Loa loa causes Loa loa filariasis also known as Calabar swelling; Mansonella streptocerca, which causes streptocerciasis, an itchy condition that creates depigmented skin lesions sometimes mistaken for the first signs of leprosy.