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  2. Adrenaline - Wikipedia

    en.wikipedia.org/wiki/Adrenaline

    Adrenaline does not readily cross the blood-brain barrier, so its effects on memory consolidation are at least partly initiated by β adrenoceptors in the periphery. Studies have found that sotalol , a β adrenoceptor antagonist that also does not readily enter the brain, blocks the enhancing effects of peripherally administered adrenaline on ...

  3. Adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_receptor

    The second hypothesis found support from 1906 to 1913, when Henry Hallett Dale explored the effects of adrenaline (which he called adrenine at the time), injected into animals, on blood pressure. Usually, adrenaline would increase the blood pressure of these animals. Although, if the animal had been exposed to ergotoxine, the blood pressure ...

  4. Beta-2 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Beta-2_adrenergic_receptor

    The beta-2 adrenergic receptor (β 2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline), a hormone and neurotransmitter whose signaling, via adenylate cyclase stimulation through trimeric G s proteins, increases cAMP, and, via downstream L-type calcium channel interaction, mediates physiologic responses such as smooth ...

  5. Alpha-2 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Alpha-2_adrenergic_receptor

    The α 2-adrenergic receptor binds both norepinephrine released by sympathetic postganglionic fibers and epinephrine (adrenaline) released by the adrenal medulla, binding norepinephrine with slightly higher affinity. [4] It has several general functions in common with the α 1-adrenergic receptor, but also has specific effects of its own.

  6. Alpha-1 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_adrenergic_receptor

    In smooth muscle cells of blood vessels the principal effect of activation of these receptors is vasoconstriction.Blood vessels with α 1-adrenergic receptors are present in the skin, the sphincters [4] of gastrointestinal system, kidney (renal artery) [5] and brain. [6]

  7. Cortisol - Wikipedia

    en.wikipedia.org/wiki/Cortisol

    Cortisol has a permissive effect on the actions of hormones that increase glucose production, such as glucagon and adrenaline. [7] Cortisol also plays an important, but indirect, role in liver and muscle glycogenolysis (the breaking down of glycogen to glucose-1-phosphate and

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