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Vaccine Excipients Adenovirus vaccine: This list refers to the type 4 and type 7 adenovirus vaccine tablets licensed in the US: Acetone, alcohol, anhydrous lactose, castor oil, cellulose acetate phthalate, dextrose, D-fructose, D-mannose, FD&C Yellow #6 aluminium lake dye, fetal bovine serum, human serum albumin, magnesium stearate, micro crystalline cellulose, plasdone C, Polacrilin potassium ...
Combined hepatitis A and B vaccine, is used to provide protection against hepatitis A and hepatitis B. [3] [7] It is given by injection into muscle.[8]It is used in areas where hepatitis A and B are endemic, for travelers, people with hepatitis C or chronic liver disease, and those at high risk of sexually transmitted diseases.
Hepatitis B vaccine is a vaccine that prevents hepatitis B. [13] The first dose is recommended within 24 hours of birth with either two or three more doses given after that. [ 13 ] This includes those with poor immune function such as from HIV/AIDS and those born premature . [ 13 ]
Hepatitis A vaccine is a vaccine that prevents hepatitis A. [ 2 ] [ 3 ] It is effective in around 95% of cases and lasts for at least twenty years and possibly a person's entire life. [ 4 ] If given, two doses are recommended beginning after the age of one. [ 2 ]
A vaccine dose contains many ingredients (such as stabilizers, adjuvants, residual inactivating ingredients, residual cell culture materials, residual antibiotics and preservatives) very little of which is the active ingredient, the immunogen. A single dose may have merely nanograms of virus particles, or micrograms of bacterial polysaccharides.
The vaccine protects against HAV in more than 95% of cases for longer than 25 years. [48] In the United States, the vaccine developed by Maurice Hilleman and his team was licensed in 1995, [49] [50] and the vaccine was first used in 1996 for children in high-risk areas, and in 1999 it was spread to areas with elevating levels of infection. [51]
The hepatitis B vaccine was the first vaccine capable of preventing cancer, specifically liver cancer. [73] Most vaccines are given in three doses over a course of days. A protective response to the vaccine is defined as an anti-HBs antibody concentration of at least 10 mIU/ml in the recipient's serum.
HBIG is indicated as a postexposure prophylaxis for people at risk to develop hepatitis B because they have been recently exposed to body fluids of individuals who have hepatitis B. This includes babies of mothers with hepatitis B, sexual partners, healthcare workers, police and fire workers, and morticians. [ 6 ]