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More children from preschool ages to preeteens are getting melatonin supplements, often for months of regular use. ... the greater the dosage: preschoolers took as much as 2 milligrams, while ...
One expert says the sleep aid is "overused" by some families.
Melatonin overdoses in kids are on the rise. A top sleep expert on inaccurate labels and what parents should do before using these supplements with their kids.
Melatonin is also available as an over-the-counter dietary supplement in many countries. It is available in both immediate-release and less commonly prolonged-release forms. The compound is available in supplements at doses ranging from 0.3 mg to 10 mg or more. It is also possible to buy raw melatonin powder by the weight. [39]
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
Then, using endogenous melatonin as a marker for circadian rhythms, several research groups showed that appropriately timed melatonin administration could entrain free-running rhythms in the totally blind: they found that 6 out of 7 patients treated with 10 mg melatonin at bedtime were normally entrained, and when the dose was gradually reduced ...