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The third ventricle is one of the four connected cerebral ventricles of the ventricular system within the mammalian brain. It is a slit-like cavity formed in the diencephalon between the two thalami , in the midline between the right and left lateral ventricles , and is filled with cerebrospinal fluid (CSF).
This is an extremely serious condition regardless of the cause of blockage. An endoscopic third ventriculostomy is a surgical procedure for the treatment of hydrocephalus in which an opening is created in the floor of the third ventricle using an endoscope placed within the ventricular system through a burr hole.
The medial surfaces form the upper part of the lateral wall to the third ventricle. In humans, it is only about one centimeter long – though in females, it is about 50% larger on average. [1] Sometimes, it is in two parts – and 20% of the time, it is absent. [2] In other mammals, it is larger.
The fibers of the oculomotor nerve arise from a nucleus in the midbrain, which lies in the gray substance of the floor of the cerebral aqueduct and extends in front of the aqueduct for a short distance into the floor of the third ventricle.
In a study of 12 healthy males with average age 17 years, MRI scans showed mean whole thalamus volume 8.68cm. [ 10 ] The medial surface of the thalamus constitutes the upper part of the lateral wall of the third ventricle , and is connected to the corresponding surface of the opposite thalamus by a flattened gray band, the interthalamic adhesion .
Subfornical organ of a mouse. In this photomicrograph, the subfornical organ (arrow) is located on the undersurface of the fornix in the upper part of the third ventricle. The cells in this coronal section of the brain were colored with a bluish dye ("Nissl stain"). The thalamus is at the bottom of the photo. The bar at the lower right ...
It lies within the periventricular zone and is not to be confused with the periventricular nucleus, which occupies a more medial position, beneath the third ventricle. The PVN is highly vascularised and is protected by the blood–brain barrier , although its neuroendocrine cells extend to sites (in the median eminence and in the posterior ...
In the third ventricle, there is a small amount in the roof that is continuous with that in the body, via the interventricular foramina, the channels that connect the lateral ventricles with the third ventricle. A choroid plexus is in part of the roof of the fourth ventricle.