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Mupirocin was initially isolated in 1971 from Pseudomonas fluorescens. [9] It is on the World Health Organization's List of Essential Medicines. [10] In 2022, it was the 162nd most commonly prescribed medication in the United States, with more than 3 million prescriptions. [11] [12] It is available as a generic medication. [13]
Mupirocin 2% ointment can be effective at reducing the size of lesions. A secondary covering of clothing is preferred. [79] As shown in an animal study with diabetic mice, the topical application of a mixture of sugar (70%) and 3% povidone-iodine paste is an effective agent for the treatment of diabetic ulcers with MRSA infection. [83]
First-line treatment for serious invasive infections due to MRSA is currently glycopeptide antibiotics (vancomycin and teicoplanin). A number of problems with these antibiotics occur, such as the need for intravenous administration (no oral preparation is available), toxicity, and the need to monitor drug levels regularly by blood tests.
This can also help develop new treatment strategies by researchers for more effective treatments. [9] By enriching the knowledge of commonly prescribed drugs, pharmacy students will be more familiar with their mechanism of action, first-line therapy indications and side effects.
Topical fusidic acid is occasionally used as a treatment for acne vulgaris. [7] As a treatment for acne, fusidic acid is often partially effective at improving acne symptoms. [ 8 ] However, research studies have indicated that fusidic acid is not as highly active against Cutibacterium acnes as many other antibiotics that are commonly used as ...
Burow's solution is an aqueous solution of aluminium triacetate.It is available in the U.S. as an over-the-counter drug for topical administration, with brand names including Domeboro (Moberg Pharma), Domeboro Otic (ear drops), Star-Otic, and Borofair. [1]