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Of particular importance, the presence of pseudo-lipoblasts in a myxoid sarcoma-like background is an extremely strong indicator that the tumor is a MFS. [ 6 ] and tumors with a myxofibrosarcoma-like histopathology that initiate in the retroperitoneum, abdominal cavity, or pelvis are nearly always dedifferentiated liposarcomas .
The epithelioid inflammatory myofibroblastic sarcoma subtype of IMT shows sheets of epithelioid to round cells within a myxoid (i.e. appears blue or purple compared to the normal red appearance of connective tissue when appropriately H&E stained and examined under the microscope), collagenous, or mixed myxoid-collagenous matrix, <5% spindle ...
Spindle cell sarcoma is a type of connective tissue cancer. The tumors generally begin in layers of connective tissue , as found under the skin, between muscles, and surrounding organs, and will generally start as a small, inflamed lump, which grows in size.
A myxoid tumor is a connective tissue tumor with a "myxoid" background, composed of clear, mucoid substance. [1] Atrial myxoma. This tumoral phenotype is shared by many tumoral entities: Myxomas. Atrial myxoma; Odontogenic myxoma; Cutaneous myxoma; Intramuscular myxoma; Myxoid hamartoma; Aggressive angiomyxoma; Myxoid leiomyoma; Chondromyxoid ...
This lesion was first described in 1998 independently in three publications which named the disorder "acral myxoinflammatory fibroblastic sarcoma", [19] "inflammatory myxoid tumor of the soft parts with bizarre giant cells", [20] and "inflammatory myxohyaline tumor of distal extremities with virocyte or Reed-Sternberg-like cells".
Post-treatment local recurrences and metastases were observed in 15% and 38% of cases; 5- and 10-year overall survival rates were 60% and 48%, respectively; Overall median survival time were 10.1 years; and patients with tumors ≥10 cm in longest diameter had an almost 6-fold higher rate of developing metastases than patients with tumors 4 cm ...
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