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Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; [1] this may be measured by echocardiography or cardiac catheterization.
Tirzepatide has demonstrated significant benefits in obese patients with a common type of heart failure, preserved ejection fraction (HFpEF) in a phase III trial. [ 25 ] [ 26 ] Over two years, tirzepatide reduced the risk of major complications, including urgent heart failure visits, hospitalizations, increased diuretic treatment, and ...
N-terminal pro-BNP (NT-proBNP) is the favored biomarker for the diagnosis of heart failure, according to guidelines published 2018 by NICE in the UK. [3] Brain natriuretic peptide 32 (BNP) is another biomarker commonly tested for heart failure. [74] [6] [75] An elevated NT-proBNP or BNP is a specific test indicative of heart failure ...
In a series of videos, the man responsible for the deadly New Year’s attack in New Orleans discussed planning to kill his family and having dreams that helped inspire him to join ISIS, according ...
Production of the Ram 1500 TRX truck wrapped up at the end of 2023, according to a statement from the company, but the automaker celebrated the model with a special edition for the 2024 model year ...
Funding for the city's fire department decreased by $17.6 million, or 2%, between the 2024-25 fiscal year and the 2023-24 fiscal year, according to city budget documents. However, the city council ...
[10] [11] [18] To investigate its use for heart failure in those with a preserved LVEF (HFpEF), Novartis funded the PARAGON-HF trial which was designed to investigate the use of sacubitril/valsartan in the treatment of HFpEF patients with a LVEF of 45% or more. Concluding in 2019, it failed to show significance for reducing hospitalisation ...
A drug trafficking investigation in Bogalusa, Louisiana, has led to the arrest of the city's mayor, Tyrin Truong, and several other people, police said Tuesday.
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