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Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. Distal expansion of the long bones as well as painful, swollen joints [ 3 ] and synovial villous proliferation are often seen.
[20] [21] [22] Rheumatoid nodulosis, which may occur in joint areas, can vary in its effect on hand function. [23] Milder cases often do not disturb daily function, whereas severe ones may induce loss-of-function. [23] Besides this, gouty arthritis can be associated with tophi deposits in the joints of the hand. [22] Gout can induce pain and ...
The most common symptoms are joint pain and stiffness. [1] Usually the symptoms progress slowly over years. [1] Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs. [1]
The TMC joint is a synovial joint between the trapezium bone of the wrist and the metacarpal bone at the base of the thumb. This joint is a so-called saddle joint (articulatio sellaris), unlike the CMC joints of the other four fingers which are ellipsoid joints. [17] This means that the surfaces of the TMC joint are both concave and convex.
RS3PE typically involves the joints of the extremities, specifically the metacarpophalangeal and proximal interphalangeal joints, wrists, shoulders, elbows, knees and ankles. [4] It is more common in older adults, with the mean age between 70 and 80 years in most studies. [4] [5] It occurs more often in men than in women with a 2:1 ratio.
It typically results in warm, swollen, and painful joints. [1] Pain and stiffness often worsen following rest. [1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. [1] The disease may also affect other parts of the body, including skin, eyes, lungs, heart, nerves, and blood. [1]
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