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Bile acid malabsorption (BAM), known also as bile acid diarrhea, is a cause of several gut-related problems, the main one being chronic diarrhea.It has also been called bile acid-induced diarrhea, cholerheic or choleretic enteropathy, bile salt diarrhea or bile salt malabsorption.
Chronic diarrhea may be caused by excess bile salts entering the colon rather than being absorbed at the end of the small intestine (the ileum). This condition of bile acid malabsorption occurs after surgery to the ileum, in Crohn's disease, with a number of other gastrointestinal causes, or is commonly a primary, idiopathic condition.
These conjugated bile acids are often referred to as bile salts. The pKa of the unconjugated bile acids are between 5 and 6.5, [ 4 ] and the pH of the duodenum ranges between 3 and 5, so when unconjugated bile acids are in the duodenum, they are almost always protonated (HA form), which makes them relatively insoluble in water.
(Here are 12 other reasons why you might be having for diarrhea.) ... The liver produces bile, which assists in nutrient absorption, including fat absorption. Failure to produce bile, or enough ...
Diarrhea can be prevented by improved sanitation, clean drinking water, and hand washing with soap. [2] Breastfeeding for at least six months and vaccination against rotavirus is also recommended. [2] Oral rehydration solution (ORS)—clean water with modest amounts of salts and sugar—is the treatment of choice. [2] Zinc tablets are also ...
High Fiber Foods. You should rethink eating foods like beans and broccoli until you reach your destination. While good for your body in general, fiber can cause gas and bloating. Digestion of high ...
Colestyramine is also used in the control of other types of bile acid diarrhea. The primary, idiopathic form of bile acid diarrhea is a common cause of chronic functional diarrhea, often misdiagnosed as diarrhea-predominant irritable bowel syndrome (IBS-D), and most of these patients respond to colestyramine. [4]
“A kidney cell might be exposed to different patterns of salts, fluids, nutrients; based on those patterns, it might change how it acts in the future. One known example of this kind of memory is ...