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2. Lubiprostone - Wikipedia

   en.wikipedia.org/wiki/Lubiprostone

   Lubiprostone, sold under the brand name Amitiza among others, is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation. The drug is owned by Mallinckrodt and is marketed by Takeda Pharmaceutical Company.

3. Plecanatide - Wikipedia

   en.wikipedia.org/wiki/Plecanatide

   Plecanatide, sold under the brand name Trulance, is a medication for the treatment of chronic idiopathic constipation (CIC) [4] and irritable bowel syndrome with constipation. [5] It is available in India under the brand name Plectide (OQM Div, MSN Laboratories, India). Plecanatide is an agonist of guanylate cyclase-C.

4. Sucampo and Abbott Announce Launch of AMITIZA in Japan - AOL

   www.aol.com/news/2012-11-26-sucampo-and-abbott...

   AMITIZA is approved in the United States for the treatment of two constipation-related indications, and in Switzerland and the United Kingdom for one constipation-related indication.

5. Laxative - Wikipedia

   en.wikipedia.org/wiki/Laxative

   They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have. Certain stimulant, lubricant, and saline laxatives are used to evacuate the colon for rectal and bowel examinations, and may be supplemented by enemas under certain circumstances. Sufficiently high doses of laxatives may cause ...

6. U.S. Food and Drug Administration Grants Priority Review ...

   www.aol.com/2012/09/25/us-food-and-drug...

   U.S. Food and Drug Administration Grants Priority Review Status to AMITIZA ® (lubiprostone) Submission Seeking Approval for Treatment of Opioid-induced Constipation BETHESDA, Md. & DEERFIELD, Ill ...

7. Constipation - Wikipedia

   en.wikipedia.org/wiki/Constipation

   Constipation is more concerning when there is weight loss or anemia, blood is present in the stool, there is a history of inflammatory bowel disease or colon cancer in a person's family, or it is of new onset in someone who is older. [12] Treatment of constipation depends on the underlying cause and the duration that it has been present. [4]