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  2. Davenport diagram - Wikipedia

    en.wikipedia.org/wiki/Davenport_diagram

    Once equilibrium is reached, the pH and bicarbonate concentration are measured and plotted on a chart as in Fig. 3. Next, the P CO 2 in the chamber is held constant while the pH of the blood sample is changed, first by adding a strong acid, then by adding a strong base. As pH is varied, a titration curve for the sample is produced (Fig. 4).

  3. Leveling effect - Wikipedia

    en.wikipedia.org/wiki/Leveling_effect

    The strength of a strong acid is limited ("leveled") by the basicity of the solvent. Similarly the strength of a strong base is leveled by the acidity of the solvent. When a strong acid is dissolved in water, it reacts with it to form hydronium ion (H 3 O +). [2] An example of this would be the following reaction, where "HA" is the strong acid:

  4. Peter A. Stewart - Wikipedia

    en.wikipedia.org/wiki/Peter_A._Stewart

    Peter Arthur Robert Stewart (1921–1993) was a Canadian physiologist who introduced an alternate approach to understanding acidbase physiology.. He outlined his model in a paper in 1978, [1] and explained it his 1981 book, How to Understand AcidBase. [2]

  5. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acidbase_homeostasis

    An acid-base diagram for human plasma, showing the effects on the plasma pH when P CO 2 in mmHg or Standard Base Excess (SBE) occur in excess or are deficient in the plasma [23] Acidbase imbalance occurs when a significant insult causes the blood pH to shift out of the normal range (7.32 to 7.42 [16]).

  6. Acid–base disorder - Wikipedia

    en.wikipedia.org/wiki/Acidbase_disorder

    Acidbase imbalance is an abnormality of the human body's normal balance of acids and bases that causes the plasma pH to deviate out of the normal range (7.35 to 7.45). In the fetus, the normal range differs based on which umbilical vessel is sampled (umbilical vein pH is normally 7.25 to 7.45; umbilical artery pH is normally 7.18 to 7.38). [1]

  7. Delta ratio - Wikipedia

    en.wikipedia.org/wiki/Delta_Ratio

    When this happens the numerator is large, the denominator is small, and the result is a delta ratio which is high (>2). This means a combined high anion gap metabolic acidosis and a pre-existing either respiratory acidosis or metabolic alkalosis (causing the high bicarbonate) – i.e. a mixed acidbase metabolic acidosis. [citation needed]

  8. Respiratory acidosis - Wikipedia

    en.wikipedia.org/wiki/Respiratory_acidosis

    Acute respiratory acidosis occurs when an abrupt failure of ventilation occurs. This failure in ventilation may be caused by depression of the central respiratory center by cerebral disease or drugs, inability to ventilate adequately due to neuromuscular disease (e.g., myasthenia gravis, amyotrophic lateral sclerosis, Guillain–Barré syndrome, muscular dystrophy), or airway obstruction ...

  9. Titration curve - Wikipedia

    en.wikipedia.org/wiki/Titration_curve

    A typical titration curve of a diprotic acid, oxalic acid, titrated with a strong base, sodium hydroxide.Both equivalence points are visible. Titrations are often recorded on graphs called titration curves, which generally contain the volume of the titrant as the independent variable and the pH of the solution as the dependent variable (because it changes depending on the composition of the ...