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Potassium binders are medications that bind potassium ions in the gastrointestinal tract, thereby preventing its intestinal absorption. This category formerly consisted solely of polystyrene sulfonate, a polyanionic resin attached to a cation, administered either orally or by retention enema to patients who are at risk of developing hyperkalaemia (abnormal high serum potassium levels).
Polystyrene sulfonates are a group of medications used to treat high blood potassium. [1] Effects generally take hours to days. [1] They are also used to remove potassium, calcium, and sodium from solutions in technical applications. Common side effects include loss of appetite, gastrointestinal upset, constipation, and low blood calcium. [1]
Initial treatment in those with ECG changes is salts, such as calcium gluconate or calcium chloride. [1] [3] Other medications used to rapidly reduce blood potassium levels include insulin with dextrose, salbutamol, and sodium bicarbonate. [1] [5] Medications that might worsen the condition should be stopped and a low potassium diet should be ...
However, if hyperkalemia causes any ECG change it is considered a medical emergency [12] due to a risk of potentially fatal abnormal heart rhythms and is treated urgently. [12] Potassium levels greater than 6.5 to 7.0 mmol/L in the absence of ECG changes are managed aggressively. [12] Several approaches are used to treat hyperkalemia. [12]
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AstraZeneca's (AZN) Lokelma secures an FDA approval for the treatment of hyperkalemia in adults. Skip to main content. Subscriptions; Animals. Business. Entertainment. Fitness. Food ...