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Illustration of a melanocyte Micrograph of melanocytes in the epidermis. Through a process called melanogenesis, melanocytes produce melanin, which is a pigment found in the skin, eyes, hair, nasal cavity, and inner ear. This melanogenesis leads to a long-lasting pigmentation, which is in contrast to the pigmentation that originates from ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 11 February 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
Albinism occurs when melanocytes produce little melanin. This albino girl is from Papua New Guinea. In humans, melanin is the primary determinant of skin color. It is also found in hair, the pigmented tissue underlying the iris of the eye, and the stria vascularis of the inner ear.
A melanocytic nevus (also known as nevocytic nevus, nevus-cell nevus, and commonly as a mole) [1] [2] is usually a noncancerous condition of pigment-producing skin cells. It is a type of melanocytic tumor that contains nevus cells. [2]
The dermis contains two vascular networks that run parallel to the skin surface—one superficial and one deep plexus—which are connected by vertical communicating vessels. [8] [11] The function of blood vessels within the dermis is fourfold: to supply nutrition, to regulate temperature, to modulate inflammation, and to participate in wound ...
Micrograph of keratinocytes, basal cells and melanocytes in the epidermis Keratinocytes (stained green) in the skin of a mouse. Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells. [1]
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
Both of these conditions originate from the same type of cell: the melanocyte. However, a melanocytic nevus is benign, and melanoma is malignant. Most melanocytic nevi never evolve into a cancer, with the lifetime risk for an individual nevus being 1 in 3000 for men and 1 in 11 000 for women. [5]