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If the template has a separate documentation page (usually called "Template:template name/doc"), add [[Category:Medical symptoms and signs templates]] to the <includeonly> section at the bottom of that page. Otherwise, add <noinclude>[[Category:Medical symptoms and signs templates]]</noinclude>
To induce general anesthesia, propofol is the drug used almost exclusively, having largely replaced sodium thiopental. [13]It is often administered as part of an anesthesia maintenance technique called total intravenous anesthesia, using either manually programmed infusion pumps or computer-controlled infusion pumps in a process called target controlled infusion (TCI).
General anesthesia drugs such as midazolam, ketamine, propofol and fentanyl are used to put a person in a twilight state or render them completely unconscious and unaware of pain. Dentists who have completed a training program in anesthesiology may also administer general IV and inhalation anesthetic agents.
Propofol, an anesthetic medication, confers its own antiemetic properties. Weibel, Rücker, Eberhart et al's 2020 Cochrane review demonstrated that combination therapy is more effective than single anti-emetic, and that dexamethasone and ondansetron (a commonly used combination) are two of the most effective anti-emetics for PONV.
[1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals. Because most people are not diagnostically trained or knowledgeable, they typically describe their symptoms in layman's terms, rather than using specific medical terminology. This list is not exhaustive.
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Propofol is also painful when administered intravenously, therefore, lidocaine is commonly used as a pretreatment to help decrease the pain associated with administering propofol. [ dubious – discuss ] Additionally, it [ clarification needed ] has antiemetic properties that are also useful in these types of procedures.
Propofol (di-isopropyl phenol) was synthesized by Glen and colleagues in the early 1970s, [7] but its first formulations were temporarily withdrawn due to a number of adverse reactions during clinical studies. [1] In 1983, a lipid emulsion formulation of propofol was available, which carried great potential during clinical trials. [8]