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Abnormally excessive or synchronous neuronal activity in the brain can cause seizures. These symptoms are characteristic of the neurological disorder known as epilepsy. Epilepsy is typically diagnosed with an EEG test. [6] However, the effectiveness of MEG in the diagnosis of neocortical epilepsy has also been established. [7]
The EEG has been used for many purposes besides the conventional uses of clinical diagnosis and conventional cognitive neuroscience. An early use was during World War II by the U.S. Army Air Corps to screen out pilots in danger of having seizures; [116] long-term EEG recordings in epilepsy patients are still used today for seizure prediction.
Forced Normalization (FN) is a psychiatric phenomenon in which a long term episodic epilepsy or migraine disorder is treated, and, although the electroencephalogram (EEG) appears to have stabilized, acute behavioral, mood, and psychological disturbances begin to manifest.
Intracerebral electrodes are placed within the desired brain areas to record the electrical activity during epileptic seizures, thus contributing to define with accuracy the boundaries of the "epileptogenic zone", i.e. the area of brain generating the seizures which should be eventually surgically resected to achieve freedom from epileptic ...
A paper published in 2023 showed that burst suppression and epilepsy may share the same ephaptic coupling mechanism. [6] When inhibitory control is sufficiently low, as in the case of certain general anesthetics such as sevoflurane (due to a decrease in the firing of interneurons [7]), electric fields are able to recruit neighboring cells to fire synchronously, in a burst suppression pattern.
A spike-and-wave discharge is a regular, symmetrical, generalized EEG pattern seen particularly during absence epilepsy, also known as ‘petit mal’ epilepsy. [1] The basic mechanisms underlying these patterns are complex and involve part of the cerebral cortex , the thalamocortical network , and intrinsic neuronal mechanisms.